Study concept and design: Koton, Schneider, Rosamond, Coresh.
Acquisition, analysis, or interpretation of data: Koton, Schneider, Rosamond, Shahar, Sang, Gottesman.
Drafting of the manuscript: Koton, Coresh.
Critical revision of the manuscript for important intellectual content: Koton, Schneider, Shahar, Sang, Gottesman, Rosamond, Coresh.
Statistical analysis: Koton, Schneider, Sang, Coresh.
Obtained funding: Rosamond, Coresh.
Administrative, technical, or material support: Sang.
Study supervision: Koton, Coresh.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: The Atherosclerosis Risk in Communities (ARIC) study is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute (NHLBI) contracts (HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, and HHSN268201100012C) with neurocognitive studies supported by U01 HL096812, HL096814, HL096899, HL096902, HL096917, and with previous brain magnetic resonance imaging examinations funded by R01-HL70825. Dr Schneider reports receipt of grant support from the National Institutes of Health (NIH)/NHLBI T32 HL007024. Dr Gottesman reports receit of grant support from NIH/NHLBI R01 AG040282.
Role of the Sponsors: NHLBI staff participate in ARIC committees including design and conduct of the study; funders did not participate in collection, management, analysis, and interpretation of the data; nor preparation, review, or approval of the manuscript and the decision to submit the manuscript for publication.
Additional Contributions: The authors thank the staff and participants of the ARIC study for their important contributions.