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Guidelines for Managing High Blood Pressure

Wendy S. Klein, MD1; C. Noel Bairey Merz, MD2; Marjorie R. Jenkins, MD3
[+] Author Affiliations
1Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond
2Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California
3Department of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo
JAMA. 2014;312(3):294-295. doi:10.1001/jama.2014.6593.
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To the Editor The updated 2014 guidelines for the management of high BP in adults by the panel appointed to the JNC 81 did not consider issues relevant to sex differences in hypertensive health. Variables of age and race were addressed, but stratification by sex was omitted. Sex is a determinant of health outcomes, with differences in metabolism, hormonal milieu, pharmacodynamics, pathophysiology, and therapeutic considerations.


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July 16, 2014
Eduardo Ortiz, MD, MPH; Suzanne Oparil, MD; Paul A. James, MD
1Rockville, Maryland4Dr Ortiz was with the National Heart, Lung, and Blood Institute, Bethesda, Maryland, at the time of the project
2University of Alabama at Birmingham School of Medicine
3University of Iowa, Iowa City
JAMA. 2014;312(3):295-296. doi:10.1001/jama.2014.6599.
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