Study concept and design: Li, Dixon, Prakash, Lam, Garg.
Acquisition, analysis, or interpretation of data: Li, Dixon, Prakash, Kim, Knoll, Lam, Garg.
Drafting of the manuscript: Li, Prakash, Lam, Garg.
Critical revision of the manuscript for important intellectual content: Li, Dixon, Kim, Knoll, Lam, Garg.
Statistical analysis: Li, Dixon, Kim, Knoll, Garg.
Obtained funding: Li, Prakash, Garg.
Administrative, technical, or material support: Li, Prakash, Garg.
Study supervision: Garg.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Ms Prakash is the Vice President of Operations at Ontario’s organ procurement organization, Trillium Gift of Life Network. Dr Kim reported receiving investigator-initiated research grants from Astellas Canada, Novartis Canada, and Genzyme Canada. Dr Knoll reported receiving investigator-initiated research grants from Astellas Canada and Wyeth/Pfizer Canada. Dr Garg reported receiving an investigator-initiated grant from Astellas and Roche to support a Canadian Institutes of Health Research study in living kidney donors. No other disclosures were reported.
Funding/Support: This Institute for Clinical Evaluative Sciences (ICES) project was conducted by the provincial Kidney, Dialysis, and Transplantation program. ICES is funded by an annual grant from the Ontario Ministry of Health and Long-term Care, and the Kidney, Dialysis, and Transplantation program is funded by an operating grant from the Canadian Institutes of Health Research. Core funding for ICES Western is provided by the Academic Medical Organization of Southwestern Ontario, the Schulich School of Medicine and Dentistry, Western University, and the Lawson Health Research Institute. Mr Li is supported by an Allied Health Doctoral Fellowship from the Kidney Foundation of Canada. Dr Lam is supported by a KRESCENT postdoctoral fellowship award and the Clinical Investigator Program at Western University.
Role of the Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The opinions, results, and conclusions are those of the authors and are independent from the funding sources. No endorsement by these organizations is intended or should be inferred.
Additional Contributions: We thank Nelson Chong, BSc, and Charlotte Ma, BEng, for linking the datasets; Karey Iron, MHSc, for helping obtain organ and tissue donor registration data; and Craig Nathanson, PhD, for helping obtain data from the College of Physicians and Surgeons of Ontario. None received compensation for their role in the study.