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Influence of Chronic Kidney Disease on Warfarin Therapy for Atrial Fibrillation

Rahman Shah, MD1; Kirsten M. Roberts, PharmD2; Kodangudi B. Ramanathan, MD1
[+] Author Affiliations
1Section of Cardiovascular Medicine, University of Tennessee School of Medicine, Memphis
2Veterans Affairs Medical Center, Memphis, Tennessee
JAMA. 2014;311(24):2542. doi:10.1001/jama.2014.5581.
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To the Editor Several randomized trials and meta-analyses have shown that the risk of bleeding is significantly higher for warfarin anticoagulation therapy than for treatment with aspirin.1,2 However, in the study by Dr Carrero and colleagues,3 the authors concluded that warfarin use was not associated with an increased risk of bleeding, compared with no warfarin, in patients with CKD.


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June 25, 2014
Juan Jesús Carrero, PhD(Pharm and Med); Karolina Szummer, MD, PhD; Tomas Jernberg, MD, PhD
1Division of Renal Medicine, Karolinska Institutet, Stockholm, Sweden
2Division of Cardiology, Karolinska Institutet, Stockholm, Sweden
JAMA. 2014;311(24):2542-2543. doi:10.1001/jama.2014.5587.
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