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Comment & Response |

Home-Based Exercise and Hip Fracture Rehabilitation—Reply

Nancy K. Latham, PhD, PT1; Jonathan F. Bean, MD, MS, MPH2; Alan M. Jette, PhD, PT1
[+] Author Affiliations
1Health and Disability Research Institute, Boston University School of Public Health, Boston, Massachusetts
2Spaulding Rehabilitation Hospital Network, Boston, Massachusetts
JAMA. 2014;311(23):2440-2441. doi:10.1001/jama.2014.5173.
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In Reply Dr Safer and colleagues identify several variables (vitamin D, nutritional status, and sarcopenia) that were not part of the full baseline assessment in our study. We acknowledge that these are among a number of variables that could potentially be associated with function after hip fracture, and that this could result in confounding if these variables were unevenly distributed between the intervention and control groups.

To minimize the potential for confounding, we used concealed and stratified randomization in the trial, which resulted in the intervention and control groups being balanced in all measures of comorbid conditions, demographic characteristics, impairments, and functional performance. At baseline, no significant differences between the intervention and control group were detected for muscle strength, mobility, or other physical performance measures that are associated with sarcopenia and vitamin D levels in older adults.1


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June 18, 2014
Umut Safer, MD; Ilker Tasci, MD; Vildan Binay Safer, MD
1Department of Geriatrics, Gulhane School of Medicine, Ankara, Turkey
2Department of Internal Medicine, Gulhane School of Medicine, Ankara, Turkey
3Department of Physical Medicine and Rehabilitation, Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey
JAMA. 2014;311(23):2440. doi:10.1001/jama.2014.5170.
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