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Commentary |

The Crisis in Clinical Research:  Endangering the Half-Century National Institutes of Health Consensus

Alan N. Schechter, MD
JAMA. 1998;280(16):1440-1442. doi:10.1001/jama.280.16.1440.
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Writing in THE JOURNAL in October 1952, Dr Norman H. Topping, associate director of the National Institutes of Health (NIH), announced the construction of the Clinical Center for medical research in Bethesda, Md, with these words:

Topping NH.The United States Public Health Service's Clinical Center for Medical Research. JAMA.1952;150:541-545.
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Bush V.Science, the Endless Frontier: A Report to the President on a Program for Postwar Scientific Research .Washington, DC: US Government Printing Office; 1945.
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Nathan DG.for the National Institutes of Health Director's Panel on Clinical Research. Clinical research: perceptions, reality, and proposed solutions. JAMA.1998;280:1427-1431.
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Institute of Medicine. Scientific Opportunities and Public Needs .Washington, DC: National Academy Press; 1998. Available at: http://www.nap.edu/readingroom/books/nih. Accessed July 1998.

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