Year after year, uncontrolled studies are published that attempt to
compare the various treatments for localized prostate cancer. Almost uniformly,
more questions are raised than answered and the debate goes on: Is surgery
the most effective treatment? How comparable are surgery, external radiotherapy,
and interstitial radiation delievered by implant (brachytherapy)? What is
the marginal benefit of any treatment over conservative management followed
by delayed hormone therapy? Two articles in this issue of THE JOURNAL, one
by Albertsen et al1 and one by D'Amico et al,2 add more information but still leave physicians and
their patients without definitive answers to these pressing questions.
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