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Comment & Response |

Left Atrial Fibrosis and Recurrent Arrhythmia

Laurens F. Tops, MD, PhD1; Martin J. Schalij, MD, PhD1
[+] Author Affiliations
1Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands
JAMA. 2014;311(22):2335. doi:10.1001/jama.2014.5184.
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To the Editor In the Delayed-Enhancement MRI Determinant of Successful Radiofrequency Catheter Ablation of Atrial Fibrillation (DECAAF) study, Dr Marrouche and colleagues1 demonstrated that assessment of left atrial fibrosis with delayed enhancement magnetic resonance imaging (MRI) was associated with the likelihood of recurrent arrhythmia after catheter ablation for atrial fibrillation (AF). It is well recognized that the outcome of catheter ablation procedures depends on appropriate patient selection and the exact ablation strategy.2 To what extent then does the DECAAF study truly add incremental value for optimal patient selection and individualized ablation strategy?


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June 11, 2014
Nassir Marrouche, MD
1Comprehensive Arrhythmia Research and Management Center, University of Utah Health Sciences, Salt Lake City
JAMA. 2014;311(22):2335-12336. doi:10.1001/jama.2014.5187.
February 5, 2014
Nassir F. Marrouche, MD; David Wilber, MD; Gerhard Hindricks, MD; Pierre Jais, MD; Nazem Akoum, MD; Francis Marchlinski, MD; Eugene Kholmovski, PhD; Nathan Burgon, BSc; Nan Hu, PhD; Lluis Mont, MD; Thomas Deneke, MD; Mattias Duytschaever, MD; Thomas Neumann, MD; Moussa Mansour, MD; Christian Mahnkopf, MD; Bengt Herweg, MD; Emile Daoud, MD; Erik Wissner, MD; Paul Bansmann, MD; Johannes Brachmann, MD
1Comprehensive Arrhythmia and Research Management Center, University of Utah School of Medicine, Salt Lake City
2Loyola University Medical Center, Maywood, Illinois
3University of Leipzig, Leipzig, Germany
4Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France
5Hospital of the University of Pennsylvania, Philadelphia
6University of Barcelona, Barcelona, Spain
7BG-Kliniken Bergmannsheil, University of Bochum, Bochum, Germany
8University Hospital Ghent, Ghent, Belgium
9Kerckhoff Heart Center, Bad Nauheim, Germany
10Massachusetts General Hospital, Boston
11Klinikum Coburg GmbH, II, Medizinische Klinik, Coburg, Germany
12Morsani College of Medicine, University of South Florida, Tampa
13Ohio State University, Columbus
14Asklepios Klinik St Georg, Hamburg, Germany
15Medical Center Porz am Rhein, Cologne, Germany
JAMA. 2014;311(5):498-506. doi:10.1001/jama.2014.3.
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