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Comment & Response |

Guidelines for Cardiovascular Risk Assessment and Cholesterol Treatment—Reply

Victor M. Montori, MD, MSc1; Juan P. Brito, MD1; Henry H. Ting, MD, MBA1
[+] Author Affiliations
1Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, Minnesota
JAMA. 2014;311(21):2236. doi:10.1001/jama.2014.4078.
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In Reply We agree with Dr Lloyd-Jones and colleagues that the ACC/AHA cholesterol guidelines1,2 represent progress by redirecting the focus from reducing low-density lipoprotein cholesterol levels to reducing cardiovascular risk and by promoting personalized decisions about statin use. Although the guideline literally recommends “Initiation of statin therapy for patients who are eligible for primary CVD prevention and have a predicted 10-year hard AS[atherosclerotic]CVD risk of ≥7.5%,”2(p36,Table) our Viewpoint advocated for inviting at-risk patients to engage in shared decision making about statins to reduce their risk for ASCVD.


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June 4, 2014
Donald M. Lloyd-Jones, MD, ScM; David C. Goff Jr, MD, PhD; Neil J. Stone, MD
1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
2Colorado School of Public Health, Denver, Colorado
3Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
JAMA. 2014;311(21):2235. doi:10.1001/jama.2014.4072.
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