0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
From the Centers for Disease Control and Prevention |

Silicosis Deaths Among Young Adults—United States, 1968-1994 FREE

JAMA. 1998;280(1):13-14. doi:10.1001/jama.280.1.13.
Text Size: A A A
Published online

MMWR. 1998;47:331-335

2 figures omitted

Silicosis is a potentially fatal and typically chronic fibrotic lung disease caused by occupational exposure to respirable crystalline silica dust.1 In the United States, most silicosis-associated deaths occur among persons aged ≥65 years,2 often following many years of silica dust exposure. However, the continuing occurrence of silicosis deaths in young adults reflects relatively recent overexposures, some of sufficient magnitude to cause severe disease and death after relatively short periods of exposure. This report describes deaths among two young adults with silicosis and underscores the risk for deaths from silicosis at relatively young ages.

CASE REPORTS

Two sandblasters died from progressive massive fibrosis (PMF), an advanced form of silicosis, following intensive dust exposure during abrasive sandblasting of oil field pipes and tanks in western Texas.3 The first death occurred in a 36-year-old man who had worked as a sandblaster for 36 months from 1984 to 1988, when PMF was diagnosed. He died from respiratory failure in 1995, 11 years after his initial exposure. The second death occurred in a 30-year-old man who had worked as a sandblaster for 48 months during 1986-1990. He died from respiratory failure in 1996, 10 years after initial exposure.

At diagnosis, each worker had radiographic evidence of severe silicosis; one underwent a lung biopsy that revealed silicotic nodules and fibrosis. Autopsies for both revealed grey and hard upper and middle lobes of the lungs, with multiple small nodules palpable in the lower lobes. Microscopic examination revealed widespread interstitial inflammation and fibrosis, and mineralogic analysis revealed extremely high silica particle content.

MORTALITY SURVEILLANCE TRENDS

Using CDC's National Center for Health Statistics (NCHS) multiple cause-of-death data files for all U.S. deaths from 1968 through 1994, presumptive silicosis deaths were identified using International Classification of Diseases (ICD) codes* listed as either an underlying or contributing cause of death among persons aged ≥15 years. Descriptive analyses were conducted using three age groups (15-44 years, 45-64 years, and ≥65 years). Usual industry and occupation, coded in accordance with Bureau of Census industry and occupation codes, were examined in the NCHS data files.

During 1968-1994, a total of 14,824 silicosis-associated deaths were recorded; 11,250 (75.9%) occurred among persons aged ≥65 years, 3367 (22.7%) among persons aged 45-64 years, and 207 (1.4%) among persons aged 15-44 years. Overall, silicosis deaths declined substantially from 1157 in 1968 to <400 annually after 1980. Among young persons (i.e., aged 15-44 years), deaths from silicosis declined less during 1968-1994. Young silicosis decedents resided in 38 states and the District of Columbia; 17 (8.2%) were aged 15-24 years; 40 (19.3%), aged 25-34 years; and 150 (72.5%), aged 35-44 years.

Among young silicosis decedents, 57.0% were white, and 90.8% were male. Among silicosis decedents aged ≥65 years, 90.0% were white, and 98.1% were male. The proportion of decedents of races other than white generally increased during 1968-1994 in both the 45-64 and ≥65 age groups, but remained relatively stable among young decedents. In all three age groups, the proportion of female decedents generally increased. Of the nine silicosis deaths that occurred among young women during 1985-1994, six were of races other than white.

Reporting to NCHS of the "usual" industry and occupation of decedents began in 1985, with varying numbers of states (range: 16-22 states) providing this information in that and subsequent years. Of the 59 young silicosis decedents during 1985-1994, a total of 25 (42.4%) died in a year for which their state of residence provided decedents' employment information to NCHS. Construction and manufacturing were coded most frequently as the usual industry (28.0% each); no deaths were attributed to mining. In comparison, among 897 silicosis decedents aged ≥65 years, manufacturing accounted for 46.2%, mining for 21.1%, and construction for 9.5% of deaths. Usual occupations for the 25 young silicosis decedents included operators of various machines used to crush, grind, mix, and blend materials (six [24.0%]); painters/paint spray operators (five [20.0%]); construction trades (four [16.0%]); and laborers, except construction (four [16.0%]).

Reported by:

Div of Respiratory Disease Studies, National Institute for Occupational Safety and Health; and an EIS officer, CDC.

CDC Editorial Note:

Primary prevention of silicosis through exposure control is important because no effective medical treatment exists for this disease, which continues to progress even after a worker is removed from further exposure.4 Despite the existence of legally enforceable limits on worker exposure to respirable crystalline silica dust, overexposures of sufficient magnitude to cause premature deaths continue to occur in the United States. Silicosis latency and rate of progression correlate with intensity of exposure5; extremely high exposures are associated with much shorter latency and more rapid disease progression. Consequently, silicosis-associated deaths in young persons generally result from more recent and intense exposure to silica dust.

The sex, racial, and employment differences between young and older silicosis decedents presented in this report may reflect changes in both workforce demographics and industrial activity over recent decades, especially given the increasing proportion of females among young silicosis decedents. The high, but temporally constant, proportion of minorities among young silicosis decedents may reflect the generally higher levels of dust to which minority workers have been exposed.6,7 For example, in the foundry industry, higher levels of silica dust exposure accounted for apparently higher risk for silicosis among black workers than among white workers.7

Extreme overexposures to respirable silica have been documented during sandblasting5 and in the construction industry.8 Abrasive blasting with silica sand, often used to prepare surfaces for painting, has been associated with exposures up to 200 times the CDC's National Institute for Occupational Safety and Health (NIOSH)-recommended exposure limit for respirable crystalline silica dust (0.05 mg/m3).5 NIOSH has recommended that silica sand be prohibited as an abrasive blasting agent.5

The findings in this report are subject to several limitations. The ICD code used to identify presumptive silicosis is not entirely specific for silicosis, and cause-of-death coding errors can occur. However, a review of a sample of death certificates of 10 young decedents in whom silicosis was presumptively diagnosed found that only two were not attributable to silicosis. In addition, many states do not provide decedents' employment data to NCHS, and the Census employment codes lack substantial detail. Even when recorded accurately and coded appropriately, silicosis decedents' usual employment does not always represent employment relevant to silica exposure. Finally, the NCHS data lack personal identifiers necessary for follow-back to confirm silicosis as cause of death, to ascertain details about occupational exposure to silica dust, and to investigate specific workplaces for potential ongoing hazardous exposure.

The Sentinel Event Notification System for Occupational Risks (SENSOR) program† and a preexisting surveillance program in New Jersey have demonstrated that identifying silicosis deaths from state mortality data files is one of several useful case-ascertainment methods for state-based silicosis surveillance and related preventive intervention.9 Although implementation of all silicosis case ascertainment methods and case follow-up activities field-tested through SENSOR may be optimal, state health departments often do not have sufficient resources for a comprehensive approach.

In 1997, the Council of State and Territorial Epidemiologists adopted a resolution recommending that silicosis be made a reportable condition. Regardless of reporting requirement status, state health departments can initiate active efforts in silicosis prevention by identifying silicosis deaths through annual review of state mortality data and giving priority to investigation of circumstances surrounding those that occur at younger ages. Additional information about silicosis prevention activities and technical assistance for worksite investigations and other follow-back activities are available from NIOSH, telephone (304) 285-6115.

ARTICLE INFORMATION

*The Eighth Revision (ICD-8) codes 010 and 515.0 were used for 1968-1978, and the Ninth Revision (ICD-9) code 502 was used for 1979-1994.
† The SENSOR program, involving cooperative agreements between NIOSH and state health departments, is designed to develop and field test surveillance and intervention strategies for selected occupational conditions.

REFERENCES

American Thoracic Society, Adverse effects of crystalline silica exposure. Am J Respir Crit Care Med. 1997;155761- 5
Link to Article
National Institute for Occupational Safety and Health, Work-related lung disease surveillance report 1996.  Cincinnati, Ohio US Department of Health and Human Services, Public Health Service, CDC1996;DHHS publication no. (NIOSH)96-134.
Abraham  JLWiesenfeld  SL Two cases of fatal PMF in an ongoing epidemic of accelerated silicosis in oilfield sandblasters: lung pathology and mineralogy. Ann Occup Hyg. 1997;41 ((suppl 1)) 440- 7
Link to Article
Kreiss  KZhen  B Risk of silicosis in a Colorado mining community. Am J Ind Med. 1996;30529- 39
Link to Article
National Institute for Occupational Safety and Health, Alert: request for assistance in preventing silicosis and deaths from sandblasting.  Cincinnati, Ohio US Department of Health and Human Services, Public Health Service, CDC1992;DHHS publication no. (NIOSH)92-102.
CDC, Silicosis: cluster in sandblasters—Texas, and occupational surveillance for silicosis. MMWR. 1990;39433- 6
Rosenman  KDReilly  MJRice  CHertzberg  VTseng  C-YAnderson  HA Silicosis among foundry workers: implication for the need to revise the OSHA standard. Am J Epidemiol. 1996;144890- 900
Link to Article
National Institute for Occupational Safety and Health, Alert: request for assistance in preventing silicosis and deaths in construction workers.  Cincinnati, Ohio US Department of Health and Human Services, Public Health Service, CDC1996;DHHS publication no. (NIOSH)96-112.
Valiante  DJRosenman  KD Does silicosis still occur? JAMA. 1989;2623003- 6
Link to Article

Figures

Tables

References

American Thoracic Society, Adverse effects of crystalline silica exposure. Am J Respir Crit Care Med. 1997;155761- 5
Link to Article
National Institute for Occupational Safety and Health, Work-related lung disease surveillance report 1996.  Cincinnati, Ohio US Department of Health and Human Services, Public Health Service, CDC1996;DHHS publication no. (NIOSH)96-134.
Abraham  JLWiesenfeld  SL Two cases of fatal PMF in an ongoing epidemic of accelerated silicosis in oilfield sandblasters: lung pathology and mineralogy. Ann Occup Hyg. 1997;41 ((suppl 1)) 440- 7
Link to Article
Kreiss  KZhen  B Risk of silicosis in a Colorado mining community. Am J Ind Med. 1996;30529- 39
Link to Article
National Institute for Occupational Safety and Health, Alert: request for assistance in preventing silicosis and deaths from sandblasting.  Cincinnati, Ohio US Department of Health and Human Services, Public Health Service, CDC1992;DHHS publication no. (NIOSH)92-102.
CDC, Silicosis: cluster in sandblasters—Texas, and occupational surveillance for silicosis. MMWR. 1990;39433- 6
Rosenman  KDReilly  MJRice  CHertzberg  VTseng  C-YAnderson  HA Silicosis among foundry workers: implication for the need to revise the OSHA standard. Am J Epidemiol. 1996;144890- 900
Link to Article
National Institute for Occupational Safety and Health, Alert: request for assistance in preventing silicosis and deaths in construction workers.  Cincinnati, Ohio US Department of Health and Human Services, Public Health Service, CDC1996;DHHS publication no. (NIOSH)96-112.
Valiante  DJRosenman  KD Does silicosis still occur? JAMA. 1989;2623003- 6
Link to Article

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles