THE WORLD'S first wide-scale efficacy testing of a vaccine to prevent AIDS received the go-ahead from the Food and Drug Administration last month, although some scientists remain skeptical about its prospects for success.
The approval allows VaxGen, Inc, a South San Francisco, Calif, biotechnology company that developed the experimental vaccine, called AIDSVAX, to go forward with a 3-year, placebo-controlled phase 3 efficacy trial involving 5000 volunteers at high risk for HIV infection in as many as 40 clinics in the United States and Canada. Once the necessary approvals are secured from Thai health officials, the company expects to begin enrolling 2500 volunteers in 16 clinics in Thailand later this year in a similar trial involving a slightly different vaccine formulation.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 4
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.