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Comment & Response |

CPAP and Reduced Blood Pressure

Alejandro de la Sierra, MD1
[+] Author Affiliations
1Department of Internal Medicine, Hospital Mutua Terrassa, Terrassa, Spain
JAMA. 2014;311(19):2022. doi:10.1001/jama.2014.2673.
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To the Editor Dr Martínez-García and colleagues1 reported that continuous positive airway pressure (CPAP) reduced 24-hour mean blood pressure in patients with resistant hypertension and obstructive sleep apnea (OSA). Moreover, this intervention had favorable effects on the circadian pattern, as demonstrated by the reduction in the proportion of patients with a riser pattern.

These results are potentially important in the current management of resistant hypertension, a condition that affects a considerable proportion of patients with hypertension undergoing treatment.2 However, the effects of CPAP on the systolic and diastolic components of blood pressure were not as expected. Indeed, CPAP treatment promoted a significant reduction of 24-hour diastolic blood pressure (DBP), but the effect on systolic blood pressure (SBP) only became significant after multiple adjustments.

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May 21, 2014
Miguel Ángel Martínez-García, MD, PhD; Francisco Campos-Rodriguez, MD, PhD; Josep-Maria Montserrat, MD, PhD
1Pneumology Service, University and Polytechnic La Fe Hospital, Valencia, Spain
2Pneumology Service, Valme Hospital, Seville, Spain
3Pneumology Service, Hospital Clinic-IDIBAPS, Barcelona, Spain
JAMA. 2014;311(19):2022-2023. doi:10.1001/jama.2014.2676.
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