Author Contributions: Dr Hayes had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Hayes, Ollendorf, Pearson, Barry, Stahl, McMahon.
Acquisition of data: Hayes, Ollendorf, Pearson, Stewart, Bhatnagar, McMahon.
Analysis and interpretation of data: Hayes, Ollendorf, Pearson, Barry, Kantoff, Stewart, Sweeney, Stahl, McMahon.
Drafting of the manuscript: Hayes, Ollendorf, Pearson, Barry, Sweeney, Stahl, McMahon.
Critical revision of the manuscript for important intellectual content: Ollendorf, Pearson, Barry, Kantoff, Stewart, Bhatnagar, Stahl, McMahon.
Statistical analysis: Hayes, Ollendorf, Pearson, McMahon.
Obtained funding: Hayes, Ollendorf, Pearson, Stahl.
Administrative, technical, or material support: Ollendorf, Pearson, Sweeney, McMahon.
Study supervision: Pearson, Barry, Kantoff, Stahl.
Financial Disclosures: Dr Barry receives salary support as president of the Foundation for Informed Medical Decision Making, a not-for-profit private foundation. The foundation develops content for patient education programs, including a program on prostate cancer treatment. The foundation has an arrangement with a for-profit company, Health Dialog, to coproduce these programs. The programs are used as part of the decision support and disease management services Health Dialog provides to consumers through health care organizations and employers.
Funding/Support: This work was supported in part by grant R25 CA92203-08 from the National Cancer Institute at the National Institutes of Health, by grant W81XWH-09-1-0512 from the Department of Defense, by a Young Investigators Award to Dr Hayes from the Prostate Cancer Foundation, and in part by funding to the Institute for Clinical and Economic Review from the Blue Shield of California Foundation.
Role of the Sponsors: None of the funders had any role in the conduct of the study; in the collection, management, analysis, or interpretation of the data; or in the preparation, review, or approval of the manuscript.
Previous Presentations: A portion of this work was presented in abstract form as a poster at the American Society for Clinical Oncology (ASCO) Genitourinary Cancers Symposium, March 5-7, 2010, San Francisco, California, and at a moderated poster discussion session at the ASCO Annual Meeting, June 4-8, 2010, Chicago, Illinois.
Additional Contributions: We thank Robert M. Kaplan, PhD, Department of Health Services, University of California Los Angeles School of Public Health, for his leadership on the project eliciting the majority of the health state utilities and for his help with manuscript preparation (he received no compensation for his assistance).