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Elective Intra-aortic Balloon Pump Placement in High-Risk Percutaneous Coronary Intervention

Gen-Min Lin, MD; Kai-Min Chu, MD, PhD; Chih-Lu Han, MD, PhD
JAMA. 2010;304(20):2240-2242. doi:10.1001/jama.2010.1697.
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To the Editor: In their randomized controlled trial comparing elective intra-aortic balloon pump (IABP) counterpulsation vs no planned IABP support in high-risk percutaneous coronary intervention (PCI), Dr Perera and colleagues1 concluded that elective IABP did not reduce the incidence of major adverse cardiac and cardiovascular events (MACCE). We agree with the study design, which used composite end points analyzed over a short period, because most patients enrolled in the Balloon Pump–Assisted Coronary Intervention Study (BCIS-1) had severely impaired left ventricular systolic function and ischemic heart failure, which conferred a high risk of death within 5 years that would probably blunt any beneficial effect of IABP intervention at long-term follow-up.23

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References

November 24, 2010
Divaka Perera, MD, MRCP; Rodney Stables, DM, FRCP; Simon Redwood, MD, FRCP
JAMA. 2010;304(20):2240-2242. doi:10.1001/jama.2010.1700.
November 24, 2010
Gábor Tamás Szabó, MD; Ildikó Rácz, MD; Zsolt Koszegi, MD, PhD
JAMA. 2010;304(20):2240-2242. doi:10.1001/jama.2010.1699.
November 24, 2010
Annemarie E. Engström, MD; Krischan D. Sjauw, MD; José P. S. Henriques, MD, PhD
JAMA. 2010;304(20):2240-2242. doi:10.1001/jama.2010.1698.
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