Study concept and design: Moulton, Gu, Law, Hart, Jalink, Husien, Haider, Julian, Levine, Gallinger.
Acquisition, analysis, or interpretation of data: Moulton, Gu, Law, Tandan, Quan, Fairfull Smith, Jalink, Serrano, Hendler, Ruo, Gulenchyn, Finch, Julian, Levine, Gallinger.
Drafting of the manuscript: Moulton, Gu, Law, Julian, Levine, Gallinger.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Gu, Julian.
Obtained funding: Moulton, Levine, Gallinger.
Administrative, technical, or material support: Moulton, Gu, Law, Tandan, Jalink, Husien, Serrano, Hendler, Haider, Ruo, Gulenchyn, Finch, Gallinger.
Study supervision: Moulton, Jalink, Serrano, Julian, Levine, Gallinger.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: This study was supported by a grant-in-aid from the Ontario Ministry of Health and Long-term Care to the Ontario Clinical Oncology Group (OCOG). The OCOG is an academic trials group, which designs and coordinates clinical trials and is based at McMaster University and Hamilton Health Sciences Hospital. The funding covered OCOG’s data management and trial coordination, and stipends for the clinical sites for patient enrolment and data collection, for the nuclear medicine physicians for PET-CT reading, and for the fluorodeoxyglucose. In Canada, 18fluorodeoxyglucose is considered an investigational agent and thus the OCOG was responsible for collecting adverse event reports.
Role of the Sponsor: The Ontario Ministry of Health and Long-term Care had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank the following hepatobiliary surgeons: Paul D. Greig, MD, Sean P. Cleary, MD, Alice C. Wei, MD, and Ian D. McGilvray, MD (University Health Network, Toronto, Ontario); Natalie G. Coburn, MD, and Sherif S. Hanna, MD (Sunnybrook Health Sciences Centre, Toronto, Ontario); and Deepak P. Dath, MD, and Michael J. Marcaccio, MD (McMaster University, Hamilton Health Sciences, Hamilton, Ontario); and a medical physicist: Troy H. Farncombe, PhD (McMaster University, Hamilton Health Sciences). None of the individuals listed received compensation for their contributions.