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Letters | October 6, 2010

Arterial Hyperoxia and In-Hospital Mortality After Resuscitation From Cardiac Arrest

Steve Iscoe, PhD; Richard Beasley, DSc; Joseph A. Fisher, MD

JAMA. 2010;304(13):1440-1441. doi:10.1001/jama.2010.1397.

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To the Editor: Dr Kilgannon and colleagues¹ reported significantly increased in-hospital mortality in hyperoxic patients (arterial PO₂ >300 mm Hg) following cardiac arrest. Data suggesting a similar effect were reported 34 years ago by Rawles and Kenmure,² who found that an increased concentration of inspired oxygen may not increase oxygen delivery to the heart. Indeed, increased concentrations of inspired oxygen decrease coronary blood flow.³

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October 6, 2010

Arterial Hyperoxia and In-Hospital Mortality After Resuscitation From Cardiac Arrest

Gareth L. Ackland, MD, PhD; Alex Dyson, PhD; Mervyn Singer, MD, FRCP

JAMA. 2010;304(13):1440-1441. doi:10.1001/jama.2010.1396.

October 6, 2010

Arterial Hyperoxia and In-Hospital Mortality After Resuscitation From Cardiac Arrest—Reply

Stephen Trzeciak, MD, MPH; J. Hope Kilgannon, MD; Alan E. Jones, MD

JAMA. 2010;304(13):1440-1441. doi:10.1001/jama.2010.1398.

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Iscoe S, Beasley R, Fisher JA. Arterial Hyperoxia and In-Hospital Mortality After Resuscitation From Cardiac Arrest. JAMA. 2010;304(13):1440-1441. doi:10.1001/jama.2010.1397.

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