Author Contributions: Dr Mamede had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Mamede, Berge, Rikers, Schmidt.
Acquisition of data: Berge, Saase, Guldener.
Analysis and interpretation of data: Mamede, Gog, Berge, Rikers, Saase, Guldener, Schmidt.
Drafting of the manuscript: Mamede, Gog.
Critical revision of the manuscript for important intellectual content: Mamede, Gog, Berge, Rikers, Saase, Guldener, Schmidt.
Statistical analysis: Mamede, Gog.
Administrative, technical, or material support: Rikers, Saase, Guldener.
Study supervision: Schmidt.
Financial Disclosures: None reported.
Additional Contributions: We thank Júlio César Penaforte, MD, MSc (Hospital Geral de Fortaleza, Brazil) and João Macedo Coelho Filho, MD, PhD, (Faculty of Medicine, Federal University of Ceará, Brazil) for their permission to use the clinical cases that they prepared for previous studies, without compensation.