Author Contributions: Dr Safren had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Safren, Sprich, Otto.
Acquisition of data: Safren, Sprich, Mimiaga, Surman, Groves.
Analysis and interpretation of data: Safren, Mimiaga, Surman, Knouse, Otto.
Drafting of the manuscript: Safren, Sprich, Groves.
Critical revision of the manuscript for important intellectual content: Sprich, Mimiaga, Surman, Knouse, Otto.
Statistical analysis: Mimiaga, Otto.
Obtained funding: Safren, Sprich, Otto.
Administrative, technical, or material support: Safren, Sprich, Surman, Knouse, Groves.
Study supervision: Safren, Sprich, Surman.
Financial Disclosures: Drs Safren, Sprich, and Otto reported receiving royalty payments from Oxford University Press. Dr Surman reported receiving research support from Abbott, Alza, Cephalon, Eli Lilly, ElMinda the Hilda and Preston Davis Foundation, McNeil, Merck, New River, National Institutes of Health, Organon, Pfizer, Shire, and Takeda; being a speaker for Janssen-Ortho, McNeil, Novartis, Shire, and MGH Academy/Reed Medical Education (which receives funding from multiple pharmaceutical companies); and being a consultant or advisor for McNeil, Shire, and Takeda. Dr Knouse reported receiving consulting income from Eli Lilly. Dr Otto reported receiving consulting income from Jazz Pharmaceuticals, Organon (Schering-Plough), Pfizer, and Sanofi-Aventis; research support from Organon (Schering-Plough); and royalty payments for use of the SIGH-A from Lilly.
Funding/Support: This study was funded by National Institutes of Health grant 5R01MH69812.
Role of the Sponsors: The National Institutes of Health had no role in the design and conduct of the study, in the collection, management, analysis, and interpretation of the data, or in the preparation, review, or approval of the manuscript.
Previous Presentations: Initial (acute outcome) results were presented at the World Congress of Behavioral and Cognitive Therapies; June 2-5, 2010; Boston, Massachusetts.
Additional Contributions: We thank Joseph Biederman, MD, Thomas Spencer, MD, and Timothy Wilens, MD, for their support for this project. Each works for Massachusetts General Hospital and they did not receive any compensation for their contributions. We also thank Petra V. Duran, Christine Cooper-Vince, Jennifer Burbridge, PhD (Massachusetts General Hospital), Jonathan Lerner, PhD (Massachusetts General Hospital), Robert Knauz, PhD (Massachusetts General Hospital), Robert Dolye, MD (Massachusetts General Hospital), Carol Perlman, PhD (Massachusetts General Hospital during initial time of study, then private practice), and Tracey Rogers, PhD (private practice and Suffolk University) for assisting in carrying out the study. These individuals received financial contribution for their institutional or consulting (Perlman and Rogers) efforts. We also thank David Schoenfeld, PhD, for consultation about and assistance with biostatistical analysis during the time of grant submission and on the revision for this article. He received compensation for his institutional salary for this work through the Massachusetts General Hospital Clinical Research Program, which provides biostatistical support to investigators at Massachusetts General Hospital.