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Traumatic Brain Injury and Major Depressive Disorder

Brett D. Thombs, PhD
JAMA. 2010;304(8):857-858. doi:10.1001/jama.2010.1170.
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To the Editor: Dr Bombardier and colleagues1 reported that 53% of 559 adults hospitalized with complicated mild to severe traumatic brain injury (TBI) met criteria for major depressive disorder (MDD) during the 12 months following hospitalization. Patients were administered the Patient Health Questionnaire (PHQ-9) as many as 9 times during the 12-month follow-up and were classified as MDD cases if they met the study PHQ-9 threshold criterion at least once.

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August 25, 2010
Charles H. Bombardier, PhD; Nancy R. Temkin, PhD; Jesse R. Fann, MD, MPH
JAMA. 2010;304(8):857-858. doi:10.1001/jama.2010.1171.
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