Health care reform has invigorated the genre of comparative effectiveness. With new congressional funding to identify which clinical strategies may work best, this research is poised to inform clinical care, health care policy, and the funding of health care. Although comparative effectiveness studies also include randomized clinical trials and systematic reviews, the expanded availability of large administrative databases and electronic medical records has provided new opportunities to conduct observational studies without the traditional burden of actually having to collect data with purpose. Observational studies of the health outcomes associated with clinical strategies—drug therapies, surgical procedures, and chronic disease management—generally take 1 of 2 forms, comparative effectiveness or comparative safety, which pose different challenges.1
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 48
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Users' Guides to the Medical Literature
Odds Ratios in Studies of Treatment Effects
All results at
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.