Author Contributions: Dr Seymour had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Seymour, Kahn, Cooke, Watkins, Rea.
Acquisition of data: Seymour.
Analysis and interpretation of data: Seymour, Cooke, Watkins, Heckbert, Rea.
Drafting of the manuscript: Seymour.
Critical revision of the manuscript for important intellectual content: Kahn, Cooke, Watkins, Heckbert, Rea.
Statistical analysis: Seymour, Kahn, Cooke, Watkins.
Obtained funding: Seymour.
Study supervision: Kahn, Heckbert, Rea.
Financial Disclosures: None reported.
Funding/Support: Dr Seymour is supported in part by extramural training grant T32 NIH/HL07287 from the National Institutes of Health (NIH) and by National Center for Research Resources grant KL2 RR025015 from the NIH. Dr Kahn is supported by a career development award K23 HL082650 from the NIH. Dr Cooke is supported by the Robert Wood Johnson Foundation Clinical Scholars Program. Dr Watkins is supported by career development award K23 GM086729-01 from the NIH. Dr Heckbert is supported by grant 5UL1RR0205014 from the NIH. Dr Rea is supported by grants R01 HL088576-01A1 and R01 HL074098-01A1 from the NIH.
Role of the Sponsors: The funding agencies had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript.
Additional Contributions: We thank Bill O’Brien, Department of Epidemiology, University of Washington, for his assistance in data programming and record linkage. He did not receive compensation beyond his normal salary.