It has been nearly 3 decades since the recognition of AIDS1,2 and the discovery of its etiologic agent, the human immunodeficiency virus (HIV).3 Despite numerous scientific advances and major successes in the areas of prevention and treatment, HIV/AIDS continues to exact an enormous toll.4 Nonetheless, controlling and ultimately ending the HIV/AIDS pandemic is feasible. Such a goal will require 3 overarching elements: increasing HIV testing and availability of antiretroviral therapy (ART) for HIV-infected individuals; curing a sizeable proportion of HIV infected individuals, such that they no longer require lifelong therapy; and preventing new infections, using both previously proven strategies and a new generation of prevention tools.
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