Study concept and design: Connolly, Lang.
Acquisition, analysis, or interpretation of data: Connolly, Lang.
Drafting of the manuscript: Connolly.
Critical revision of the manuscript for important intellectual content: Connolly, Lang.
Administrative, technical, or material support: Connolly, Lang.
Study supervision: Lang.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Lang reports receiving financial compensation for consultancy work with Abbott, Abbvie, Allon Therapeutics, Avanir Pharmaceuticals, Biogen-Idec, Boehringer-Ingelheim, Ceregene, Medtronic, Merck, NeuroPhage Pharmaceuticals, Novartis, and Teva; receiving grant funding from Brain Canada, the Canadian Institutes of Health Research, the Edmond J. Safra Philanthropic Foundation, the Michael J. Fox Foundation, the National Parkinson Foundation, Parkinson Society Canada, the Tourette Syndrome Association, and the W. Garfield Weston Foundation; and receiving royalties from Cambridge University Press, Johns Hopkins Press, Saunders, and Wiley-Blackwell. No other disclosures were reported.