Author Contributions: Dr Bombardier had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Bombardier, Fann, Temkin, Esselman, Dikmen.
Acquisition of data: Bombardier, Fann, Temkin.
Analysis and interpretation of data: Bombardier, Fann, Temkin, Barber.
Drafting of the manuscript: Bombardier, Fann, Temkin, Barber.
Critical revision of the manuscript for important intellectual content: Fann, Temkin, Esselman, Dikmen.
Statistical analysis: Temkin, Barber.
Obtained funding: Bombardier, Fann, Temkin, Dikmen.
Administrative, technical, or material support: Fann, Esselman.
Study supervision: Bombardier, Fann.
Financial Disclosures: Dr Bombardier reported ownership of Pfizer stock. Dr Fann reported ownership of Pfizer and Amgen stock. Dr Temkin reported ownership of stock in Amgen and Kimberly-Clark and consultancies with or honoraria from Novartis, Celgene, Eisai, Pfizer, Par Pharmaceutical Companies, UCB, Actelion, and GlaxoSmithKline. Dr Esselman reported ownership of Eli Lilly stock. No other disclosures were reported.
Funding/Support: This work was supported by the National Center for Medical Rehabilitation Research, the National Institute of Child Health and Human Development, and National Institutes of Health grant R01 HD39415 to Drs Bombardier and Fann (co–principal investigators). Pfizer supplied masked sertraline and placebo for the controlled trial.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Disclaimer: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Medical Rehabilitation Research.
Previous Presentations: Parts of the manuscript were presented at the annual national meetings of the American Psychological Association, Rehabilitation Psychology Division; Charlotte, North Carolina; March 2007; and the Academy of Psychosomatic Medicine; Amelia Island, Florida; November 2007.
Additional Contributions: Erika Pelzer, BS, University of Washington School of Medicine, provided expert assistance and oversight in data collection efforts. She was compensated for her contributions.