Context.— The professional integrity of scientists is important to society as
a whole and particularly to disciplines such as medicine that depend heavily
on scientific advances for their progress.
Objective.— To characterize the professional norms of active scientists and compare
them with those of individuals with institutional responsibility for the conduct
Design.— A mailed survey consisting of 12 scenarios in 4 domains of research
ethics. Respondents were asked whether an act was unethical and, if so, the
degree to which they considered it unethical and to select responses and punishments
for the act.
Participants.— A total of 924 National Science Foundation research grantees in 1993
or 1994 in molecular or cellular biology and 140 representatives from the
researchers' institutions to the US Department of Health and Human Services
Office of Research Integrity.
Main Outcome Measures.— Percentage of respondents considering an act unethical and the mean
malfeasance rating on a scale of 1 to 10.
Results.— A total of 606 research grantees and 91 institutional representatives
responded to the survey (response rate of 69% of those who could be contacted).
Respondents reported a hierarchy of unethical research behaviors. The mean
malfeasance rating was unrelated to the characteristics of the investigator
performing the hypothetical act or to its consequences. Fabrication, falsification,
and plagiarism received malfeasance ratings higher than 8.6, and virtually
all thought they were unethical. Deliberately misleading statements about
a paper or failure to give proper attribution received ratings between 7 and
8. Sloppiness, oversights, conflicts of interest, and failure to share were
less serious still, receiving malfeasance ratings between 5 and 6. Institutional
representatives proposed more and different interventions and punishments
than the scientists.
Conclusions.— Surveyed scientists and institutional representatives had strong and
similar norms of professional behavior, but differed in their approaches to
an unethical act.