Author Contributions: Ms Dinan had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Dinan, Curtis, Patz, Abernethy, Shea.
Acquisition of data: Shea.
Analysis and interpretation of data: Dinan, Curtis, Hammill, Patz, Abernethy, Shea, Schulman.
Drafting of the manuscript: Dinan, Shea.
Critical revision of the manuscript for important intellectual content: Dinan, Curtis, Hammill, Patz, Abernethy, Schulman.
Statistical analysis: Dinan, Curtis, Hammill, Shea.
Administrative, technical, or material support: Dinan, Curtis, Schulman.
Study supervision: Patz, Schulman.
Financial Disclosures: Dr Curtis reported receiving research support from Allergan, Eli Lilly and Company, GlaxoSmithKline, Medtronic, Merck & Co, Johnson & Johnson (Ortho Biotech), Novartis, OSI Eyetech, and Sanofi-Aventis. Dr Curtis has made available online a detailed listing of financial disclosures (http://www.dcri.duke.edu/research/coi.jsp). Dr Schulman reported receiving research support from Actelion Pharmaceuticals, Allergan, Amgen, Arthritis Foundation, Astellas Pharma, Bristol-Myers Squibb, The Duke Endowment, Genentech, Inspire Pharmaceuticals, Johnson & Johnson, Kureha Corporation, Medtronic, Merck & Co, Nabi Biopharmaceuticals, National Patient Advocate Foundation, NovaCardia, Novartis, OSI Eyetech, Pfizer, Sanofi-Aventis, Scios, Tengion, Theravance, Thomson Healthcare, and Vertex Pharmaceuticals; receiving personal income for consulting from McKinsey & Company and the National Pharmaceutical Council; having equity in Alnylam Pharmaceuticals; having equity in and serving on the board of directors of Cancer Consultants Inc; and having equity in and serving on the executive board of Faculty Connection LLC. Dr Schulman has made available online a detailed listing of financial disclosures (http://www.dcri.duke.edu/research/coi.jsp). No other disclosures were reported.
Additional Contributions: Damon M. Seils, MA, Duke University, provided editorial assistance and manuscript preparation. Mr Seils did not receive compensation for his assistance apart from his employment at the institution where the study was conducted.