In this issue of JAMA, Van Cleave and colleagues1 present an analysis of 3 cohorts of children spanning 1988 to 2006 included in the National Longitudinal Survey of Youth (NLSY). The authors report that the prevalence of several categories of chronic illness in childhood is increasing and that these conditions arise, continue, or resolve in a highly dynamic fashion. Both findings have important implications and raise a number of significant questions.
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