Author Contributions: Dr Dorsey had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Dorsey, Moses.
Acquisition of data: de Roulet, Thompson, Reminick, Thai, White-Stellato, George.
Analysis and interpretation of data: Dorsey, de Roulet, Thompson, Reminick, Thai, White-Stellato, Beck, George, Moses.
Drafting of the manuscript: Dorsey, de Roulet, George, Moses.
Critical revision of the manuscript for important intellectual content: Dorsey, de Roulet, Thompson, Reminick, Thai, White-Stellato, Beck, George, Moses.
Statistical analysis: Thompson, Beck.
Obtained funding: Dorsey.
Administrative, technical, or material support: Dorsey, Moses.
Study supervision: Dorsey, Moses.
Financial Disclosures: Dr Dorsey reported receiving research support from industry (Amarin and Medivation Inc), the federal government (the National Institutes of Health [NIH]), foundations (American Parkinson Disease Association, CHDI Foundation Inc, Michael J. Fox Foundation for Parkinson's Research, National Parkinson Foundation, and the Robert Wood Johnson Foundation), and the American Academy of Neurology; consulting for Avid Radiopharmaceuticals Inc, Lundbeck Inc, Medtronic Inc, and Merck & Co Inc; and holding stock options in Avid Radiopharmaceuticals Inc. Dr Beck reported receiving research support from industry (Amarin and Guidant Corporation), the federal government (NIH), and foundations (CHDI Foundation Inc and National Parkinson Foundation). Dr Moses reported serving as chairman of The Alerion Institute and its associated Alerion Advisors, which conducts studies for academic institutions, foundations, and industry on research policy, and that he is a former partner of The Boston Consulting Group, which advises corporations internationally. No other disclosures were reported.
Funding/Support: This study was funded by grant KL2 RR024136 from the National Center for Research Resources, a component of the National Institutes of Health (NIH), and the NIH Roadmap for Medical Research.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; the analysis or interpretation of the data; or the preparation or final approval of the manuscript.
Additional Contributions: We thank Aaron Catlin, MS, of the Centers for Medicare & Medicaid Services, for his assistance in understanding changes in the National Health Expenditure data. Mr Catlin received no extra compensation for his assistance.
This article was corrected online for typographical errors on 1/12/2010.