The first edition of Ocular Pathology, published in 1975 by Myron Yanoff and Ben S. Fine, has become a classic reference text in ocular pathology. Within the ophthalmic pathology community it is simply known as “Yanoff and Fine.” The fifth edition was published in 2002; since then, a major change has been the death of Fine, a pioneer in the area of ophthalmic pathology. For the sixth edition, Yanoff has teamed with Joseph Sassani.
In many ways, Ocular Pathology maintains many of the features of the prior editions. The outline format, the interspersing of clinical pearls, and the extensive reference list at the end of each chapter have been continuing features. As before, the reference list for each chapter is organized according to chapter subheadings. The organization of the current edition is identical to that of previous editions. There are 18 chapters overall. Early chapters discuss the basic principles of pathology. Other chapters are organized by etiology (inflammation, trauma, diabetes mellitus, glaucoma, melanotic tumors, retinoblastoma) or according to the different ocular tissues (skin and lacrimal drainage system, conjunctiva, cornea and sclera, uvea, lens, retina, vitreous, optic nerve, and orbit). Chapters dedicated to the histopathology of specific ocular structures begin with illustrations of normal histology and anatomy, a useful feature first incorporated in the fourth edition.