Author Contributions: Dr Vauthey had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Vauthey and Loyer contributed equally as senior authors of this article.
Study concept and design: Vauthey, Loyer.
Acquisition of data: Boonsirikamchai, Maru, Kopetz, Palavecino, Kaur, Loyer.
Analysis and interpretation of data: Chun, Vauthey, Kopetz, Curley, Abdalla, Charnsangavej, Loyer.
Drafting of the manuscript: Chun, Vauthey, Kopetz, Loyer.
Critical revision of the manuscript for important intellectual content: Vauthey, Boonsirikamchai, Maru, Palavecino, Curley, Abdalla, Kaur, Charnsangavej, Loyer.
Statistical analysis: Chun, Vauthey.
Administrative, technical, or material support: Vauthey, Loyer.
Study supervision: Vauthey, Loyer.
Financial Disclosures: Dr Kopetz reports receiving research grants and honoraria from AstraZeneca and honoraria from Genentech, Roche, and Sanofi-Aventis. Dr Abdalla reports receiving honoraria from Sanofi-Aventis. Dr Vauthey reports receiving grants and honoraria from Sanofi-Aventis, Genentech, and Roche. No other authors reported disclosures.