Author Contributions: Dr Leveille had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Leveille, Shmerling, Guralnik, Lipsitz, Bean.
Acquisition of data: Leveille, Jones, Kiel, Lipsitz, Bean.
Analysis and interpretation of data: Leveille, Jones, Kiely, Hausdorff, Guralnik, Kiely, Lipsitz, Bean.
Drafting of the manuscript: Leveille, Jones, Kiely, Lipsitz.
Critical revision of the manuscript for important intellectual content: Leveille, Jones, Kiely, Hausdorff, Shmerling, Guralnik, Kiel, Bean.
Statistical analysis: Leveille, Jones, Kiely, Guralnik.
Obtained funding: Leveille, Kiel, Lipsitz.
Administrative, technical, or material support: Lipsitz, Bean.
Study supervision: Leveille, Lipsitz, Bean.
Financial Disclosures: Dr Kiel reports receiving grant support from Pfizer, Amgen, Merck, Novartis, and Hologic; consulting income from Amgen, Novartis, Merck, GlaxoSmithKline, Lilly, Procter & Gamble, Philips Lifeline, and Wyeth; and speakers' honoraria from Novartis, Merck GlaxoSmithKline, and Lilly.
Funding/Support: This research was supported by grant P01AG004390 from the National Institute on Aging Research Nursing Home Program Project. Dr Guralnik's time was funded by the Intramural Research Program, National Institute on Aging, NIH. The coding of the medication data for the MOBILIZE Boston Study was supported by an unrestricted grant from Pfizer Inc, none of which was to support salary, stipends, or other funding except for salaries for research staff who were not involved in this article.
Role of the Sponsor: Dr Guralnik, an employee of the National Institute on Aging, had no role in the decision to fund this research. He participated in the design of the study, interpretation of the analysis, and preparation of the manuscript. No employees of Pfizer Inc had any role in the conduct of this research or in the coding of the medication data.
Disclaimer: The views expressed in this article are the authors' and do not reflect those of the study sponsors.
Additional Contributions: We thank the MOBILIZE Boston research team and study participants for their time, effort, and dedication.