Author Contributions: Dr Lambracht-Washington had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Drs Lambracht-Washington and Qu contributed equally to the work presented in this article.
Study concept and design: Lambracht-Washington, Qu, Eagar, Stüve, Rosenberg.
Acquisition of data: Lambracht-Washington, Qu, Fu.
Analysis and interpretation of data: Lambracht-Washington, Eagar, Stüve, Rosenberg.
Drafting of the manuscript: Lambracht-Washington, Qu, Fu, Eagar, Stüve, Rosenberg.
Critical revision of the manuscript for important intellectual content: Lambracht-Washington, Eagar, Stüve, Rosenberg.
Statistical analysis: Lambracht-Washington.
Obtained funding: Rosenberg.
Administrative, technical, or material support: Lambracht-Washington, Qu, Fu, Eagar, Stüve.
Study supervision: Rosenberg.
Financial Disclosures: Dr Rosenberg reported receiving clinical trial grants from Elan and Pfizer; being listed as a coinventor on US patent application for “Abeta gene vaccines,” January 2009; and being assigned to the Regents of the University of Texas system. No other disclosures were reported.
Funding/Support: This study was supported by the University of Texas Southwestern Alzheimer's Disease Center, grant P30AG12300-16 from the National Institutes of Health National Institute on Aging, the Rudman Foundation, and research grant IIRG-06-24428 from the Alzheimer's Association.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Disclaimer: Dr Rosenberg, an editorial board member for JAMA, was not involved in the editorial review of or decision to publish this article.