Author Contributions: Drs Manzoni and Maule had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Manzoni, Cattani, Stolfi, Decembrino, Vagnarelli, Maule, Mostert, Pedicino, Mosca, Ferrari, Stronati, Farina.
Acquisition of data: Manzoni, Rinaldi, Cattani, Pugni, Romeo, Messner, Stolfi, Decembrino, Laforgia, Vagnarelli, Memo, Bordignon, Saia, Maule, Gallo, Mostert, Magnani, Quercia, Bollani, Pedicino, Renzullo, Betta, Mosca, Ferrari, Magaldi, Stronati, Farina.
Analysis and interpretation of data: Manzoni, Maule, Mosca, Stronati, Farina.
Drafting of the manuscript: Manzoni, Rinaldi, Cattani, Pugni, Romeo, Messner, Stolfi, Decembrino, Laforgia, Vagnarelli, Memo, Bordignon, Saia, Maule, Gallo, Mostert, Magnani, Quercia, Bollani, Pedicino, Renzullo, Betta, Mosca, Ferrari, Magaldi, Stronati.
Critical revision of the manuscript for important intellectual content: Manzoni, Mostert, Mosca, Stronati, Farina.
Statistical analysis: Manzoni, Rinaldi, Maule, Betta.
Obtained funding: Manzoni, Vagnarelli, Stronati, Farina.
Administrative, technical, or material support: Cattani, Pugni, Laforgia, Bordignon, Gallo, Renzullo.
Study supervision: Manzoni, Romeo, Messner, Stolfi, Decembrino, Saia, Mostert, Magnani, Quercia, Pedicino, Mosca, Ferrari, Magaldi, Stronati.
Financial Disclosures: Dr Manzoni reported receiving 2 travel grants (in 2008 and 2009) from Dicofarm SpA. No other authors reported disclosures.
Funding/Support: Dicofarm SpA supported this study with a grant and supplied the drugs and placebo used in the study.
Role of the Sponsor: Dicofarm SpA had no role in the study design and enrollment of patients; the collection, analysis, and interpretation of the data; or the preparation and submission of the manuscript.
Independent Statistical Analysis: The independent statistical analysis was performed by Dr Maule, Department of Biomedical Sciences and Human Oncology, Cancer Epidemiology Unit, University of Torino, Italy. Dr Maule received no compensation or funding for conducting the analysis.
Italian Task Force for the Study and Prevention of Neonatal Fungal Infections; the Italian Society of Neonatology: In addition to the bylined authors, the task force includes the following persons: Amelia Di Comite, Alessandro Borghesi, Chryssoula Tzialla (Neonatal Intensive Care Unit [NICU], IRCCS S. Matteo, Pavia); Giovanni Agriesti, Riccardo Arisio, Giovanna Gomirato, Chiara Giovannozzi (NICU, S. Anna Hospital, Torino); Domenico Cipolla (NICU, University of Palermo); Fabio Natale (NICU, La Sapienza University, Roma); Giuseppina Corona (NICU, University of Messina); Francesco Tumminelli (NICU, Umberto I Hospital, Enna); Gennaro Vetrano (NICU, Fatebenefratelli Hospital, Benevento); Elisabetta Tridapalli (NICU, University of Bologna); Stefano Vitale (Neonatology Policlinico Casilino, Roma); Elio Caliendo (NICU, “San Giovanni di Dio e Ruggi d’Aragona” Hospital, Salerno).
Previous Presentation: Some data from this study were presented in abstract form as preliminary data at the Pediatric Academic Societies Meetings (May 2-5, 2008; Honolulu, Hawaii; and May 2-4, 2009; Baltimore, Maryland); at the First International Congress of the Union of European Neonatal and Perinatal Societies (November 17-19, 2008; Rome, Italy); and at the 48th ICAAC–46th IDSA Conference (October 24-28, 2008;Washington, DC).