0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorial |

Lactoferrin Supplementation to Prevent Nosocomial Infections in Preterm Infants

David A. Kaufman, MD
JAMA. 2009;302(13):1467-1468. doi:10.1001/jama.2009.1449.
Text Size: A A A
Published online

Extract

The study by Manzoni and colleagues1 in this issue of JAMA represents an important step toward preventing infections that currently pose a major hurdle for preterm infants. The findings give insight into the role of lactoferrin in preventing infection, helping to define its importance in breast milk as well as the effect of daily supplementation with bovine lactoferrin (BLF) in preterm infants.

The incidence of late-onset (>72 hours of age) bloodstream infections in very low-birth-weight (VLBW) infants (<1500 g) is approximately 20% and is complicated by high mortality and neurodevelopmental impairment.2,3 In the United States, nearly 65 000 VLBW infants are born each year, which translates into approximately 13 000 infections, 2300 deaths, and neurodevelopmental impairment in 3000 survivors.4 For the smallest infants of extremely low birth weight (ELBW) (<1000 g), neurodevelopmental impairment occurs in 45% of those who survive bacteremia and 57% of those who survive fungemia.3 For VLBW infants, bloodstream infections increase hospital treatment costs and length of stay.5

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles
Jobs
JAMAevidence.com
brightcove.createExperiences();