Author Contributions: Dr Schnuelle had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Schnuelle, Gottmann, Hoeger, Boesebeck, Lauchart, Weiss, Yard.
Acquisition of data: Schnuelle, Boesebeck, Lauchart, Fischereder, Jauch, Heemann, Zeier, Hugo, Pisarski, Krämer, Lopau, Rahmel.
Analysis and interpretation of data: Schnuelle, Gottmann, Benck, Birck, Yard.
Drafting of the manuscript: Schnuelle.
Critical revision of the manuscript for important intellectual content: Schnuelle, Gottmann, Hoeger, Boesebeck, Lauchart, Weiss, Fischereder, Jauch, Heemann, Zeier, Hugo, Pisarski, Krämer, Lopau, Rahmel, Benck, Birck, Yard.
Statistical analysis: Schnuelle, Weiss.
Obtained funding: Schnuelle.
Administrative, technical, or material support: Boesebeck, Lauchart, Lopau, Rahmel.
Study supervision: Schnuelle, Boesebeck, Lauchart.
Financial Disclosures: None reported.
Funding/Support: The study was an investigator-driven clinical trial conducted by the University Medical Centre of Mannheim, Germany. It was partially supported by a medical school grant from Novartis Pharmaceuticals released in November 2002, before the study started recruiting eligible donors.
Role of the Sponsor: The sponsor had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: This article is dedicated to the memory of Professor Fokko van der Woude. The following individuals participated in the study: former director of Eurotransplant International Foundation Guido Persijn, MD, PhD, and Eurotransplant staff members Jan de Boer, MD, and Mike Smith, MSc, Leiden, the Netherlands; transplant coordinators Angelika Eder, MD; Reiner Ehrhardt, MD; Alexandra Greser, MD; Margarethe von Kramolin, MD; Andreas Reif, MD; Stefan Rohmer; Siglinde Schäffner-Rehbein, MD; Susanne Schmidt, DSO, region of Bavaria, Munich, Germany; Christopher Beynon; Katharina Dette; Oliver Emmler; Carl-Ludwig Fischer-Fröhlich, MD; Erich Frey; Barbara Hornikel; Christoph Krenzel; Franz Schaub; Martina Schimmer; Christian Thurow; Monika Weber; Gerd Weissenberger, DSO, region of Baden-Württemberg, Stuttgart, Germany; and administrative personnel Sylvia Bechtel, Martha Frey, Heike Martins, University Medical Centre, Mannheim. Joanne van der Woude, PhD, Harvard University, Boston, Massachusetts, and John H. Clorius, MD, PhD, German Cancer Research Center, Heidelberg, proofread the manuscript; Hinrich Bitter-Suermann, MD, PhD, University Medical Centre, Mannheim, provided helpful comments; and all 60 collaborating transplantation centers within Eurotransplant made invaluable contributions to this study. None of the collaborators listed here were compensated for their contributions.