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Research Letter |

Childhood History of Resolved Glomerular Disease and Risk of Hypertension During Adulthood

Asaf Vivante, MD1; Gilad Twig, MD, PhD1; Amir Tirosh, MD, PhD2; Karl Skorecki, MD3; Ronit Calderon-Margalit, MD, MPH4
[+] Author Affiliations
1Talpiot Medical Leadership Program, IDF Medical Corps, Tel-Hashomer, Israel
2Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts
3Department of Nephrology, Rappaport Faculty of Medicine and Research Institute, Technion, Israel
4Hadassah-Hebrew University Braun School of Public Health, Jerusalem, Israel
JAMA. 2014;311(11):1155-1157. doi:10.1001/jama.2013.284310.
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Most children who develop glomerular disease have a favorable prognosis with complete resolution of all signs and symptoms. Yet the long-term sequelae of resolved childhood glomerular disease are incompletely understood. We assessed whether a medical history of resolved childhood glomerular disease confers a future risk for hypertension.

Section Editor: Jody W. Zylke, MD, Senior Editor.

Article InformationCorresponding Author: Asaf Vivante, MD, Talpiot Medical Leadership Program, IDF Medical Corps, Sheba Medical Center, Tel Hashomer 52621, Israel (asafvivante@gmail.com).

Author Contributions: Drs Vivante and Calderon-Margalit had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Vivante, Twig, Skorecki, Calderon-Margalit.

Acquisition of data: Vivante, Tirosh, Calderon-Margalit.

Analysis and interpretation of data: Vivante, Tirosh, Skorecki, Calderon-Margalit.

Drafting of the manuscript: Vivante, Calderon-Margalit.

Critical revision of the manuscript for important intellectual content: Vivante, Twig, Tirosh, Skorecki, Calderon-Margalit.

Statistical analysis: Vivante, Tirosh, Calderon-Margalit.

Administrative, technical, and material support: Vivante.

Study supervision: Vivante, Skorecki.

Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Skorecki reported serving as a consultant to Elsevier. Dr Calderon-Margalit reported receiving travel reimbursement from COST. No other disclosures were reported.

Funding/Support: Access to anonymized databases was provided by the Israeli Defense Forces Medical Corps.

Role of the Sponsor: The Israeli Defense Forces Medical Corps had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Additional Contributions: We thank Dorit Tzur, MBA (IDF Medical Corps), for technical support and thoughtful comments. She was not compensated for her contributions.

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