Author Contributions: Dr Regge had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Regge, Galatola, Bonelli, Bruzzi, Senore, Gandini.
Acquisition of data: Regge, Laudi, Galatola, Angelelli, Asnaghi, Barbaro, Bartolozzi, Bielen, Boni, Borghi, Cassinis, Galia, Gallo, Grasso, Laghi, Martina, Neri, Simonetti, Venturini, Gandini.
Analysis and interpretation of data: Regge, Laudi, Galatola, Della Monica, Bonelli, Barbaro, Bartolozzi, Boni, Bruzzi, Hassan, Neri, Simonetti, Venturini, Gandini.
Drafting of the manuscript: Regge, Laudi, Galatola, Della Monica, Bonelli, Angelelli, Boni, Borghi, Bruzzi, Galia, Gallo, Senore, Simonetti, Venturini.
Critical revision of the manuscript for important intellectual content: Regge, Laudi, Galatola, Asnaghi, Barbaro, Bartolozzi, Bielen, Boni, Cassinis, Grasso, Hassan, Laghi, Martina, Neri, Gandini.
Statistical analysis: Laudi, Della Monica, Bonelli, Boni, Bruzzi.
Obtained funding: Regge.
Administrative, technical, or material support: Regge, Barbaro, Bartolozzi, Borghi, Grasso, Simonetti, Venturini, Gandini.
Study supervision: Laudi, Galatola, Barbaro, Hassan, Gandini.
Financial Disclosures: None reported.
Funding/Support: This study was funded by a grant from the AIRC (Italian Association for Cancer Research) for 2005 through 2007, a grant for Progetti di Ricerca Finalizzata from Regione Piemonte, the Fondazione Cassa di Risparmio di Torino, and the Compagnia di San Paolo. The study was also endorsed by the Italian Society of Medical Radiology (SIRM) and the Italian Society of Gastroenterology (SIGE).
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: The following individuals collaborated on the acquisition of the data: Carlo Neumaier, MD; Jessica Bianucci, MD, Radiology Unit, and Emanuele Meroni, MD; Alberto Fasoli, MD, Endoscopy Unit, National Institute for Cancer Research, Genoa, Italy; Andrea Ferraris, MD, Radiology Department, and Giorgio Saracco, MD; Mario Rizzetto, MD; Gastroenterology Department, University of Turin, San Giovanni Battista Hospital, Turin, Italy; Francesca Cerri, MD, Radiology Department, University of Pisa, Italy; Pietro Occhipinti, MD; Silvia Saettone, MD, Gastroenterology Unit, SS Trinità Hospital, Borgomanero, Novara, Italy; Sandro Morassut, MD; Luca Ballestreri, MD, Radiology Unit, and Renato Cannizzaro, MD; Mara Fornasarig, MD, Gastroenterology Unit, National Cancer Institute, Aviano, Pordenone, Italy; Amato Antonio Stabile Ianora, MD; Pasquale Pedote, MD, Radiology Department, and Giuseppe Carbotta, MD; Onofrio Caputi, MD, Surgery Department, University of Bari, Policlinico Hospital, Bari, Italy; Alberto Martegani, MD, Radiology Unit, and Giorgio Minoli, MD; Giancarlo Spinzi, MD, Gastroenterology Unit, Valduce Hospital, Como, Italy; Roberto Fiori, MD, Radiology Department, Tor Vergata University, Rome, Italy; Lorenzo Bonomo, MD; Carmen Tebala, MD, Radiology Department; Maria Elena Riccioni, MD, Surgical Endoscopy Department; and Claudio Coco, MD, Surgery Department, University Cattolica, Policlinico Agostino Gemelli, Rome; Massimo Midiri, MD; Giuseppe Lo Re, MD, Radiology Department, and Francesco D’Arpa, MD; Rita Machì, MD, Endoscopy Department, University of Palermo, Policlinico Paolo Giaccone, Palermo, Italy; and Paul Rutgeerts, MD, Gastroenterology Department, University of Leuven, UZ Gasthuisberg, Leuven, Belgium. Nereo Segnan, MD, CPO Piemonte, ASO San Giovanni Battista, Turin, collaborated on the design of the study. None of these individuals received compensation for their contributions beyond their salaries.