0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Mortality in Patients With Hypovolemic Shock Treated With Colloids or Crystalloids—Reply

Djillali Annane, MD, PhD1; Sylvie Chevret, MD, PhD2
[+] Author Affiliations
1Raymond Poincaré Hospital, University of Versailles, Garches, France
2Saint Louis Hospital, Paris, France
JAMA. 2014;311(10):1069-1070. doi:10.1001/jama.2014.841.
Text Size: A A A
Published online

Extract

In Reply Dr Perner and colleagues suggest that allocation concealment was not ensured in the CRISTAL trial. However, procedures were in place to hide the allocation sequence until assignment. Sequentially numbered, sealed, and opaque envelopes were used. An envelope assigned to a patient was opened only after the investigator wrote patient information on it. The signed inclusion sheet with patient and randomization details was faxed to the coordinating center, allowing monitoring of treatment allocation to unique patients in appropriate order. Only 6 errors in envelope assignment were found, corresponding to simultaneous inclusion of a patient by multiple investigators in the same center. This process ensured a low risk of bias.1

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

March 12, 2014
Anders Perner, MD, PhD; Nicolai Haase, MD, PhD; Jørn Wetterslev, MD, PhD
1Intensive Care Medicine, Copenhagen University Hospital, Copenhagen, Denmark
JAMA. 2014;311(10):1067. doi:10.1001/jama.2014.830.
March 12, 2014
Rinaldo Bellomo, MD, FCICM; Simon Finfer, MD, FCICM; John Myburgh, PhD, FCICM
1Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia
2George Institute for Global Health, University of Sydney, Sydney, Australia
JAMA. 2014;311(10):1067-1068. doi:10.1001/jama.2014.833.
March 12, 2014
Christian Brun-Buisson, MD; Junfeng Sun, PhD; Charles Natanson, MD
1Service de Réanimation Médicale, GH Henri Mondor, Créteil, France
2Department of Critical Care Medicine, National Institutes of Health Clinical Center, Bethesda, Maryland
JAMA. 2014;311(10):1068-1069. doi:10.1001/jama.2014.836.
CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Jobs
brightcove.createExperiences();