Some of the most wrenching treatment decisions facing clinicians in developing nations involve patients with such neglected tropical diseases as human African trypanosomiasis, often called sleeping sickness. Diagnosis and treatment may include painful lumbar puncture and injections of toxic melarsoprol, an arsenic derivative that causes intense burning sensations and, in about 5% who take it, fatal encephalopathy.
“Doctors and nurses in the field are forced to care for patients with treatments that are largely archaic, toxic, ineffective; some are unaffordable and some are nonexistent,” said Sophie Delaunay, executive director of the US section of the humanitarian medical group Médecins Sans Frontières (MSF; Doctors Without Borders), as she described the challenges of neglected tropical diseases.
Graphic Jump Location
The kinetoplastid diseases—Chagas disease, human African trypanosomiasis, and leishmaniasis—lack safe, effective treatments as well as sufficient research and development funding. A recent study showed they received $125 million in funding in 2007, compared with nearly $2 billion for HIV/AIDS, tuberculosis, and malaria.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 1
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.