Author Contributions: Dr Wackers had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Young, Wackers, Chyun, Inzucchi.
Acquisition of data: Young, Wackers, Chyun, Davey, Barrett, Taillefer, Heller, Iskandrian, Wittlin, Filipchuk, Ratner, Inzucchi.
Analysis and interpretation of data: Young, Wackers, Chyun, Inzucchi.
Drafting of the manuscript: Young, Wackers, Chyun, Inzucchi.
Critical revision of the manuscript for important intellectual content: Young, Wackers, Chyun, Davey, Barrett, Taillefer, Heller, Iskandrian, Wittlin, Filipchuk, Ratner, Inzucchi.
Statistical analysis: Chyun.
Obtained funding: Wackers.
Administrative, technical, or material support: Young, Wackers, Chyun.
Study supervision: Wackers, Davey.
Ajudication of cardiac events: Young, Wackers, Chyun.
Financial Disclosures: None reported.
Funding/Support: This work was performed with the support of National Institute of Health grants M01-RR-00125 through the General Clinical Research Centers at Yale University, 5M01-RR-00847 through the University of Rochester, and 6M01-RR-05096 through Tulane University. In addition, The DIAD study was supported by grants from Bristol Myers-Squibb Medical Imaging, North Billerica, Massachusetts, and Astellas Pharma, Deerfield, Michigan, which also provided technetium-99m sestamibi and adenosine for study patients.
Role of the Sponsor: The industrial sponsors had no role in the design or conduct of the study, in the collection, analysis, or interpretation of data, or in the preparation of the manuscript.
DIAD Study Investigators:Principal Investigator and Chair: Frans J. Th. Wackers, MD (Yale University School of Medicine, New Haven, Connecticut).
Coprincipal Investigators: Lawrence H. Young, MD, Silvio E. Inzucchi, MD (Yale University School of Medicine, New Haven, Connecticut) and, Deborah A. Chyun, RN, MSN, PhD (New York University College of Nursing at the College of Dentistry, New York).
Study Coordinator: Janice A. Davey, MSN, APRN (Yale University School of Medicine, New Haven, Connecticut).
Clinical Centers: University of Montreal, Montreal, Quebec, Canada: Raymond Taillefer, MD, Sylvain Prévost, MD, Carole Benjamin, and Andre Gagnon; MedStar Research Institute, Washington, DC: Robert Ratner, MD, Maureen Passaro, MD, Evelyn Robinson, RN, and Amy Smith; Hartford Hospital, Hartford, Connecticut: Gary V. Heller, MD, PhD, Deborah Katten, RN, MPH; Tulane University, New Orleans, Louisiana: Vivian Fonseca, MD, Richard Campeau, MD, Rhonda Fontenot, RN, and Sunil Asnani, MD; University of Alabama, Birmingham: Ami E. Iskandrian, MD, Fernando Ovalle, MD, Mary Beth Hall, RN, and Misty Collins, RN; and University of Virginia, Charlottesville: Eugene Barrett, MD, George Beller, MD, Wendie Price, RN, and Denny Watson, PhD. Soundview Research Associates, Norwalk, Connecticut: Samuel Engel, MD, Mindy Sotsky, MD, Stella Carolan, RN, and Angela Martin, APRN; University of Rochester, Rochester, New York: Steven Wittlin, MD, Ronald Schwartz, MD, and Mary Kelly, RN; University of North Carolina, Chapel Hill: Elisabeth Fasy, MD, Jean Dostou, MD, Leigh Gosnell, RD, Joe Largay, Michelle Duclos, MPH, John Buse, MD, and Steven Falen, MD; MidOhio Cardiology and Vascular Consultants Columbus, Ohio: Dennis Calnon, MD, and Connie Zimmerman; Maine Cardiology Associates, Portland, Maine: Mylan Cohen, MD, and Jennifer Powers, RN; Cardiology Consultants, Calgary, Alberta, Canada: Neil Filipchuk, MD, Marie Small, RN, and Melina Krulc, RN. Kansas City Cardiology, Kansas City, Missouri: Timothy Blackburn, MD, Eric Hockstad, MD, and Terry Plesser, RN; Yale University Radionuclide Core Laboratory and Data Coordinating Center: Donna Natale, Roberta O’Brien, and Laurie Finta.
Advisory Board and Data Safety and Monitoring Board: Barry L. Zaret, MD, Section of Cardiovascular Medicine, and Robert, S. Sherwin, MD, Section of Endocrinology, Department of Internal Medicine, Yale University; and Ralph I. Horwitz, MD, Department of Internal Medicine, Stanford University, Palo Alto, California.
Additional Contributions: We thank Karen Furie, MD, MPH, Department of Neurology, Massachusetts General Hospital, Boston, who did not recieve any compensation for her contribution.
This article was corrected online for typographical errors on 4/14/2009.