To the Editor: The study by Dr Ferlin and colleagues1 advances understanding of the genetic contributions to cryptorchidism. In their study, the prevalence of Klinefelter syndrome, the most common genetic cause of cryptorchidism, was almost identical to that in a 1969 study in which the prevalence of Klinefelter syndrome among 600 boys with cryptorchidism was 1.1%.2
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