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Comment & Response |

Underrepresentation of Older Adults in Cancer Trials—Reply

Harvey Jay Cohen, MD1; Mary Naylor, PhD, RN2; Arti Hurria, MD3
[+] Author Affiliations
1Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina
2New Cortland Center for Transitions and Health, University of Pennsylvania School of Nursing, Philadelphia
3City of Hope Comprehensive Cancer Center, Duarte, California
JAMA. 2014;311(9):966-967. doi:10.1001/jama.2013.286457.
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In Reply Drs Luo and Kesselheim raise some relevant concerns regarding our Viewpoint on the IOM report entitled Delivering High-Quality Cancer Care: Charting a Course for a System in Crisis.1 Luo and Kesselheim recognize and share our concern regarding the underrepresentation of older adults in clinical trials. However, they disagree with the committee’s recommendation regarding amending patent law to provide patent exclusivity extension for companies conducting clinical trials in older adults for drugs to be used in that population, and suggest some alternative strategies.


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March 5, 2014
Jing Luo, MD; Aaron S. Kesselheim, MD, JD, MPH
1Yale Primary Care Internal Medicine Residency Program, Yale School of Medicine, New Haven, Connecticut
2Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women’s Hospital, Boston, Massachusetts
JAMA. 2014;311(9):965-966. doi:10.1001/jama.2013.286454.
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