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Book and Media Reviews |

Orthopedic Pathology

Hue H. Luu, MD
JAMA. 2009;301(6):672-677. doi:10.1001/jama.2009.65.
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This well-organized text on orthopedic pathology discusses topics ranging from metabolic bone disease to bone tumors. The text is comprehensive in that it has dedicated chapters for most orthopedic conditions, tumorous and nontumorous. While some existing orthopedic pathology texts focus primarily on musculoskeletal tumors, this text dedicates appropriate attention to important topics such as basic bone biology, metabolic bone diseases, orthopedic infections, and implant pathology. Although the text seems directed toward residents-in-training in orthopedics, pathology, and radiology, it can be a useful and worthwhile reference for practicing physicians in these respective fields. The organization allows for easy reference of any particular topic of interest.

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A, Malignant bone tumor: Ewing sarcoma. Left, Anteroposterior radiograph of left femur in a 27-year-old man. Right, Photomicrograph demonstrating small, monotonous, round cells with no significant stromal tissue (periodic acid–Schiff stain). Ewing cells are positive on periodic acid–Schiff staining; that is, they demonstrate the presence of glycogen. B, Benign bone tumor: giant cell tumor. Left, Radiograph showing an expansive, destructive tumor affecting the proximal right tibia in a teenaged female. Right, Photomicrograph demonstrating field of short spindle-shaped mononuclear stromal cells with the classic appearance of multinucleated giant cells scattered throughout the specimen (hematoxylin and eosin stain). Radiographs and photomicrographs presented courtesy of and with permission from John L. Zeller, MD, PhD.

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