Author Contributions: Dr Oeffinger had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Oeffinger, Robison, Diller, Hudson, Mertens, Leisenring.
Acquisition of data: Leisenring, Robison, Oeffinger.
Statistical analysis: Moskowitz, Leisenring, Chou.
Analysis and interpretation of data: Moskowitz, Leisenring, Oeffinger, Ford, Robison, Diller, Hudson, Mertens, Henderson, Friedman, Chou, Smith.
Drafting of the manuscript: Oeffinger.
Critical revision of the manuscript for important intellectual content: Oeffinger, Robison, Moskowitz, Leisenring, Ford, Diller, Hudson, Mertens, Henderson, Friedman, Chou, Smith.
Obtained funding: Oeffinger, Robison.
Study supervision: Oeffinger, Robison.
Financial Disclosures: None reported.
Funding/Support: This work was supported by grants R21-CA-106972 (Dr Oeffinger, principal investigator) from the National Cancer Institute, Department of Health and Human Services and the Centers for Disease Control and Prevention; U24-CA-55727 (Dr Robison, principal investigator) from the Department of Health and Human Services; funding to the University of Minnesota from the Children's Cancer Research Fund; and funding to St Jude Children's Research Hospital from the American Lebanese Syrian Associated Charities.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
The CCSS is a collaborative, multi-institutional project, funded as a resource by the National Cancer Institute. The cohort was assembled through the efforts of 26 participating clinical research centers in the United States and Canada. The study is currently funded by a U24 resource grant awarded to St Jude Children's Research Hospital. For information on contributing centers and how to access and use the CCSS resource, visit http://www.stjude.org/ccss.