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Letters |

Thyroid-Stimulating Hormone–Receptor Antibody and Thyroid Hormone Concentrations in Smokers vs Nonsmokers With Graves Disease Treated With Carbimazole

JAMA. 2009;301(2):162-164. doi:10.1001/jama.2008.931.
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Letters Section Editor: Robert M. Golub, MD, Senior Editor.

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Figure. Thyroid-Stimulating Hormone (TSH)–Receptor Antibody and Thyroid Hormone Concentrations in Smokers and Nonsmokers With Graves Disease During Treatment With Carbimazole
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Means at each time point are shown for serum concentrations of TSH-receptor antibodies (A), free thyroxine (FT4 ) (B), and total triiodothyronine (T3) (C) in smokers (n = 25) and nonsmokers (n = 34) during the first 12 months of carbimazole therapy. Area under the curve comparisons yielded  = .02 for TSH-receptor antibodies,  = .01 for FT4, and  = .003 for T3. Error bars represent 95% confidence intervals. To convert FT4 to pmol/L, multiply by 12.871; to convert T3 to nmol/L, multiply by 0.0154.

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