Developing effective treatment for obesity is a public health priority. In a randomized, 16-week trial that involved 57 overweight and obese adults, Volpp and colleagues assessed the effect of financial incentives for meeting weight loss goals on overall weight loss. The study incentives were either dollar-for-dollar investments matched to a participant's daily contribution (which was lost if they failed to achieve weight goals) or eligibility for a daily lottery prize. The authors found that compared with usual care, which included monthly weigh-ins, the addition of either economic incentive was associated with significantly greater weight loss during the 16-week intervention. However, this weight loss was not sustained beyond the intervention period.