Epilepsy is one of the most common serious neurological conditions. According to a study by the World Health Organization, epilepsy accounts for 1% of the global burden of disease based on disability-adjusted life-years (DALYs), productive years lost due to disability or premature death.1 This is equivalent to lung cancer in men and breast cancer in women. Among primary disorders of the brain, epilepsy ranks with depression and other affective disorders, Alzheimer disease and other dementias, and substance abuse. Of the world's population, 0.5% to 1.0% has active epilepsy, and pharmacotherapy is unsuccessful in controlling seizures in 20% to 40% of patients.2 In the United States, 80% of the cost of epilepsy is attributable to patients with medically intractable seizures.3 Temporal lobe epilepsy is the most common cause of pharmacoresistant seizures4 and may constitute half or more of the patients in the United States with medically intractable epilepsy.5 On the other hand, temporal lobe epilepsy is the form of epilepsy most easily and effectively treated with surgery; 60% to 90% of patients can expect to become free of disabling seizures postoperatively.6- 8 Appropriately applied surgical treatment, therefore, is crucial for reducing the health burden represented by epilepsy.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 35
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.