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Comment & Response |

Acute Muscle Wasting Among Critically Ill Patients

Daren Heyland, MD1; Carrie Earthman, PhD, RD2; Charlene Compher, PhD, RD3
[+] Author Affiliations
1Clinical Evaluation Research Unit, Kingston, Ontario, Canada
2Department of Food Science and Nutrition, University of Minnesota, Minneapolis
3University of Pennsylvania School of Nursing, Philadelphia
JAMA. 2014;311(6):621-622. doi:10.1001/jama.2013.285420.
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To the Editor The prospective study by Dr Puthucheary and colleagues1 characterized acute muscle wasting in patients with critical illness. We take exception to the clinical inference that protein delivery was associated with increased muscle wasting. These findings conflict with existing data that higher protein delivery is associated with improved survival, reduced infection, and improved health-related quality of life.2,3


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February 12, 2014
Zudin A. Puthucheary, MRCP; Mark J. W. McPhail, MRCP, PhD; Nicholas Hart, BSc, MRCP, PhD, FFICM
1Institute of Health and Human Performance, University College London, London, England
2Department of Hepatology and Gastroenterology, Imperial College London, London, England
3Lane Fox Respiratory Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, England
JAMA. 2014;311(6):622-623. doi:10.1001/jama.2013.285426.
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