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Letters |

Escitalopram, Problem-Solving Therapy, and Poststroke Depression

Michael Dettling, MD; Carolin Opgen-Rhein, MD; Ion Anghelescu, MD
JAMA. 2008;300(15):1757-1759. doi:10.1001/jama.300.15.1757-b.
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To the Editor: The study of prevention of poststroke depression by Dr Robinson and colleagues1 showed modest clinical effects of the SSRI escitalopram given over 12 months compared with placebo and problem-solving therapy. However, comparing the design of this study and its positive results with another poststroke depression study of the same group with negative results2 raises important questions.

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October 15, 2008
Olaf Schulte-Herbrüggen, MD; Stefan Röpke, MD
JAMA. 2008;300(15):1757-1759. doi:10.1001/jama.300.15.1757-a.
October 15, 2008
Jeffrey Lacasse, PhD; Jonathan Leo, PhD
JAMA. 2008;300(15):1757-1759. doi:10.1001/jama.300.15.1757-c.
October 15, 2008
Alice Rasmussen, MD; Jamal A. Hanash, MD; Per Bech, MD
JAMA. 2008;300(15):1757-1759. doi:10.1001/jama.300.15.1758-a.
October 15, 2008
Robert G. Robinson, MD; Ricardo E. Jorge, MD; Stephan Arndt, PhD
JAMA. 2008;300(15):1757-1759. doi:10.1001/jama.300.15.1758-b.
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