Author Contributions: Dr Spino had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Nygaard, Burgio, Meikle, Whitehead, Wu, Brody.
Acquisition of data: Nygaard, Meikle, Whitehead, Brody.
Analysis and interpretation of data: Nygaard, Barber, Kenton, Schaffer, Spino, Brody.
Drafting of the manuscript: Nygaard, Barber, Burgio, Kenton, Meikle, Schaffer, Spino, Whitehead, Wu.
Critical revision of the manuscript for important intellectual content: Nygaard, Barber, Burgio, Kenton, Meikle, Spino, Whitehead, Wu, Brody.
Statistical analysis: Spino.
Administrative, technical, or material support: Nygaard, Brody.
Study supervision: Nygaard.
Financial Disclosures: Dr Barber reported receiving research support from American Medical Systems and Pfizer, and speaking fees for American Medical Systems. Dr Burgio reported being a paid consultant for Pfizer, Astellas, GlaxoSmithKline, Eli Lilly, Ortho-McNeil, Novartis, and Merck; and receiving research support from Pfizer and Alza. Dr Kenton reported receiving research support from Pfizer. Dr Meikle, a National Institute of Child Health and Human Development (NICHD) employee, is the Pelvic Floor Disorders Network project officer. Dr Schaffer reported receiving research support from Cook Medical Inc and speaking fees from Astellas/GlaxoSmithKline. Dr Spino was employed by Pfizer until August 10, 2007. She has no ownership interests and no ongoing financial relationship with Pfizer. Dr Whitehead reported receiving research support and being a paid consultant to McNeil Pharmaceuticals (makers of Imodium). No other authors reported any financial disclosures.
Funding/Support: This work was supported by grants U01 HD41249, U10 HD41268, U10 HD41248, U10 HD41250, U10 HD41261, U10 HD41263, U10 HD41269, U10 HD41267, U10 HD54136, U10 HD54214, and U10 HD54215 from the Eunice Kennedy Shriver NICHD and funding from the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institutes of Health Office of Research on Women's Health.
Role of Sponsors: The sponsors had no role in the design and conduct of the study, in the collection, management, analysis, or interpretation of the data, or in the preparation, review, or approval of the manuscript.
The Pelvic Floor Disorders Network Members:Cleveland Clinic, Cleveland, Ohio: Mathew D. Barber, MD, MHS, principal investigator; Marie Fidela R. Paraiso, MD, co-investigator; Mark D. Walters, MD, co-investigator; J. Eric Jelovsek, MD, co-investigator; Linda McElrath, RN, research nurse; Donel Murphy, RN, MSN, coordinator research nurse; Cheryl Williams, research assistant; Duke University, Durham, North Carolina: Anthony G. Visco, MD, principal investigator; Jennifer Wu, MD, MPH, co-investigator; Alison Weidner, MD, co-investigator; Cindy Amundsen, MD, co-investigator; Mary J. Loomis, RN, BSN, research coordinator; Loyola University, Chicago, Illinois: Linda Brubaker, MD, MS, principal investigator; Kimberly Kenton, MD, MS, investigator; MaryPat FitzGerald, MD, MS, investigator; Elizabeth Mueller, MD, MSME, investigator; Kathy Marchese, RN, study coordinator; Mary Tulke, RN, study coordinator; University of Alabama at Birmingham: Holly E. Richter, PhD, MD, principal investigator; R. Edward Varner, MD, co-investigator; Robert L. Holley, MD, co-investigator; Thomas L. Wheeler, MD, co-investigator; Patricia S. Goode, MD, co-investigator; Kathryn L. Burgio, PhD, co-investigator; L. Keith Lloyd, MD, co-investigator; Alayne D. Markland, DO, co-investigator; Velria Willis, RN, BSN, research coordinator; Nancy Saxon, BSN, research nurse clinician; LaChele Ward, LPN, research specialist; Lisa S. Pair, CRNP; University of California, San Diego, and Kaiser, San Diego: Charles W. Nager, MD, principal investigator; Shawn A. Menefee, MD, co-investigator; Emily Lukacz, MD, co-investigator; Karl M. Luber, MD, co-investigator; Michael E. Albo, MD, co-investigator; Margie Kahn, MD, co-investigator; Lysa Woodall, RN, study coordinator; Giselle Zazueta-Damian, study coordinator; University of Michigan, Ann Arbor: Morton B. Brown, PhD, co-investigator; Cathie Spino, DSc, principal investigator; John T. Wei, MD, MS, co-principal investigator; Beverly Marchant, RN, BS, project manager; Donna DiFranco, BS, clinical monitor; John O.L. DeLancey, MD, co-investigator; Dee Fenner, MD, co-investigator; Nancy K. Janz, PhD, co-investigator; Wen Ye, PhD, and Zhen Chen, MS, statisticians; Yang Wang Casher, MS, database programmer; University of Texas, Southwestern: Joseph Schaffer, MD, principal investigator; Clifford Wai, MD, co-investigator; Marlene Corton, MD, co-investigator; Gary Lemack, MD, co-investigator; Kelly Moore, research coordinator; David Rahn, MD, co-investigator; Amanda White, MD, co-investigator; Shanna Atnip, NP, Margaret Hull, NP, Pam Martinez, NP, Deborah Lawson, NP; University of Utah, Salt Lake City: Ingrid Nygaard, MD, MS, principal investigator; Peggy Norton, MD, co-investigator; Linda Freeman, RN, research coordinator; Jan Baker, NP; National Institutes of Health Project Scientist: Susan Meikle, MD, MSPH.
Additional Information: The National Centers for Health Statistics acquired the data, as they actually interviewed the patients; therefore, 2005-2006 NHANES collected all data. However, Drs Nygaard, Meikle, and Whitehead and Ms Brody were responsible for spearheading the effort to add the Pelvic Floor Disorders questions to NHANES, assisting with pilot testing of questions, and assisting with training field workers on administering questions.